Q203, CAS 1334719-95-7

Formulation: A solid

Formal Name: 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]-1-piperidinyl]phenyl]methyl]-imidazo[1,2-a]pyridine-3-carboxamide

Purity: ≥98%

Formula Markup: C29H28ClF3N4O2

Formula Weight: 557

Shelf life (days): 1460

CAS Number: 1334719-95-7

Notes: Q203 is an imidazopyridine amide antibiotic.{51221} It is active against M. tuberculosis and M. ulcerans (MIC50s = 2.7 and 0.86 nM, respectively).{51221,51222} Q203 binds to the oxidation site on mitochondrial complex III, also known as cytochrome bc1 complex, and disrupts ATP synthesis in M. tuberculosis (IC50 = 1.1 nM).{51221} It reduces bacterial load, as well as the number of lung colony forming units (CFUs) and granulomatous foci in a mouse model of M. tuberculosis infection when administered at a dose of 10 mg/kg for three days.

• Artikelnummer: CAY37323-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37323-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe