R-Spondin 1

Product Description: R-Spondin 1 (RSPO-1) is a secreted growth factor that stabilizes β-catenin and enhances WNT signaling. R-Spondin 1 is expressed in many tissues and regulates female sex determination, XX gonad development, oocyte differentiation, and hematopoietic stem cell specification. R-Spondin 1 is suggested to function as a stem cell growth factor and may have therapeutic potential in the treatment of gastrointestinal diseases and chemotherapy-induced intestinal mucositis. Additionally, recombinant R-spondin 1 protein is used to initiate and maintain intestinal organoid cultures.

Growth Factor AA Sequence: RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA

• Artikelnummer: CGSGFH208-100
• Hersteller: Cell Guidance Systems
• Hersteller Artikelnummer: GFH208-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human