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Rabbit anti-Arginase 1 Recombinant Monoclonal Antibody (BLR161J)
Rabbit anti-Arginase 1 Recombinant Monoclonal Antibody [BLR161J]
Artikelnummer
BEYA700-161CF
Verpackungseinheit
100 µl
Hersteller
Bethyl Laboratories
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Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_031508.1
Uniprot ID: Q61176
Background: Arginase1 is a key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P05089].
Immunogen: Residues 1-322 (FL)
Conjugate Type: Unconjugated
Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_031508.1
Uniprot ID: Q61176
Background: Arginase1 is a key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P05089].
Immunogen: Residues 1-322 (FL)
| Artikelnummer | BEYA700-161CF |
|---|---|
| Hersteller | Bethyl Laboratories |
| Hersteller Artikelnummer | A700-161CF |
| Green Labware | Nein |
| Verpackungseinheit | 100 µl |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine) |
| Klonalität | Monoclonal |
| Methode | Immunoprecipitation, Western Blotting, Immunohistochemistry |
| Isotyp | Whole IgG |
| Human Gene ID | 11846 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
