Rabbit anti-Bcl 6 antibody, clone SQab22268 (monoclonal)

Clone Number: SQab22268

Immunogen: Recombinant fragment within Human Bcl 6.

Concentration: n/a

Format: Purification with Protein A.

Storage buffer: PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.

Additional info: Application note: IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.Storage instruction: For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Applications: IHC-P

• Artikelnummer: SANMON240272
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON240272
• Verpackungseinheit: 100 ul
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Wirt: Rabbit
• Konjugat: Unconjugated