Clone Number: EP10
Immunogen: A synthetic peptide corresponding to residues in the C-terminus of human CD117 protein.
Concentration: Greater than or equal to 13 mg/L
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117), which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST), small lung cell carcinomas and in melanomas.
References: Sawyer EJ et al. Journal of Pathology 2003, 200, 59-64