Rabbit anti-CD25/IL-2R alpha Recombinant Monoclonal Antibody (BLR157J)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_000408.1

Uniprot ID: P01589

Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. The IL2 receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [taken from NCBI Entrez Gene (Gene ID: 3559)].

Immunogen: Residues 22-213 (ECD)

• Artikelnummer: BEYA700-157CF
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A700-157CF
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunoprecipitation, Western Blotting, Immunocytochemistry
• Isotyp: Whole IgG
• Human Gene ID: 3559
• Wirt: Rabbit
• Konjugat: Unconjugated