Rabbit anti-CD279 / PD-1 antibody, clone SQab1732 (monoclonal)

Clone Number: SQab1732

Immunogen: Recombinant full length protein of Human PD‐1. The immunogen contains the specific extracellular domain of Human PD‐1 (Leu25 ‐ Gln167).

Concentration: n/a

Format: Purification with Protein A.

Storage buffer: PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.

Additional info: Application note: IHC-P: Antigen Retrieval: Boil tissue section in Tris/EDTA buffer (pH 9.0).* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.Storage instruction: For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.Background: CD279 / PD-1 is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Applications: FC, ICC/IF, IHC-P, IP

• Artikelnummer: SANMON240119
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON240119
• Verpackungseinheit: 100 ul
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Immunoprecipitation, Flow Cytometry, Immunocytochemistry
• Wirt: Rabbit
• Konjugat: Unconjugated