Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_001234.3
Uniprot ID: P28908
Background: CD30 is a member of the TNF-receptor superfamily, expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 943)].
Immunogen: Residues 19-385 (ECD)