Rabbit anti-CD4, clone EP204 (Monoclonal)

Clone Number: EP204

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: CD4 is a 55 kD glycoprotein expressed on the surface of T-helper/regulatory T-cells, monocytes, macrophages, and dendritic cells. Anti-CD4 is used in the immunophenotyping of lymphoproliferative disorders.1 The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+ CD8-.2 As with other T-cell antigens, CD4 may be aberrantly expressed in neoplastic T-cells so that the evaluation of such tumors requires the application of a panel of markers in order to identify tumors with CD4 aberrant expression.1-3

References: Leong AS-Y, et al. Greenwich Medical Media Ltd. 2003/Akiyama T, et al. Pathol Int. 2008; 58:626-34/Garcia-Herrera A, et al. J Clin Oncol. 2008; 26:3364-71

• Artikelnummer: SANMON-RTU1287
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1287
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated