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Rabbit anti-CDK5RAP3 Antibody, Affinity Purified
Rabbit anti-CDK5RAP3 Antibody, Affinity Purified
Artikelnummer
BEYA300-871A
Verpackungseinheit
100 µl
Hersteller
Bethyl Laboratories
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Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_788276.1
Uniprot ID: Q96JB5
Background: CDK5RAP3 (CDK5 regulatory subunit-associated protein 3) was identified as a protein that associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development; however CDK5RAP3 appears to be widely expressed in human tissues. CDK5RAP3 appears to exhibit functions that extend beyond its association with Cdk5. CDK5RAP3 is involved in modulating the G2/M DNA damage checkpoint and can associate with and regulate the Cdk1-cyclin B1 complex. CDK5RAP3 has also been demonstrated to interact with and regulate the tumor suppressor ARF (alternative reading frame) to further play a role in cell cycle progression.
Immunogen: Between 456 and C-terminus
Conjugate Type: Unconjugated
Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_788276.1
Uniprot ID: Q96JB5
Background: CDK5RAP3 (CDK5 regulatory subunit-associated protein 3) was identified as a protein that associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development; however CDK5RAP3 appears to be widely expressed in human tissues. CDK5RAP3 appears to exhibit functions that extend beyond its association with Cdk5. CDK5RAP3 is involved in modulating the G2/M DNA damage checkpoint and can associate with and regulate the Cdk1-cyclin B1 complex. CDK5RAP3 has also been demonstrated to interact with and regulate the tumor suppressor ARF (alternative reading frame) to further play a role in cell cycle progression.
Immunogen: Between 456 and C-terminus
| Artikelnummer | BEYA300-871A |
|---|---|
| Hersteller | Bethyl Laboratories |
| Hersteller Artikelnummer | A300-871A |
| Green Labware | Nein |
| Verpackungseinheit | 100 µl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Polyclonal |
| Methode | Immunoprecipitation, Western Blotting |
| Isotyp | Whole IgG |
| Human Gene ID | 80279 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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