Rabbit anti-COX4 antibody, clone SQab1874 (monoclonal)

Clone Number: SQab1874

Immunogen: Synthetic peptide around the N-terminus of Human COX IV.

Concentration: n/a

Format: Purification with Protein A.

Storage buffer: PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.

Additional info: Application note: IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0.* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.Storage instruction: For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.Background: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Applications: FC, ICC/IF, IHC-P, IP, WB

• Artikelnummer: SANMON240143
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON240143
• Verpackungseinheit: 100 ul
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Immunoprecipitation, Western Blotting, Flow Cytometry, Immunocytochemistry
• Wirt: Rabbit
• Konjugat: Unconjugated