Rabbit anti-CSN2 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_004227.1

Uniprot ID: P61201

Background: CSN2 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals a function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN2 has also been demonstrated to interact with the sin3A corepressor complex as well as the thyroid hormone and vitamin D3 receptor to mediate gene repression.

Immunogen: Between 1 and 50

• Artikelnummer: BEYA300-027A
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A300-027A
• Green Labware: Nein
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Western Blotting, Immunohistochemistry
• Isotyp: Whole IgG
• Human Gene ID: 9318
• Wirt: Rabbit