Rabbit anti-Human IgG4 Recombinant Monoclonal Antibody (BLR113H)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Uniprot ID: P01861

Background: IgG4 represents only 2-5% of the human IgG subclasses in serum. IgG4 lacks effector functions, such as antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity. IgG4 plays a protective role in allergy by acting as a blocking antibody, and inhibiting mast cell degranulation, but a deleterious role in malignant melanoma, by impeding IgG1-mediated anti-tumor immunity.

Immunogen: Between 75 and 125

• Artikelnummer: BEYA700-113CF
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A700-113CF
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Western Blotting, Immunohistochemistry
• Isotyp: Whole IgG
• Human Gene ID: 3503
• Wirt: Rabbit
• Konjugat: Unconjugated