Rabbit anti Human NUMB

Rabbit anti Human NUMB, Polyclonal

Background: Implicated in the control of cell fate decisions during development. Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.

Positive Control: Protein found in brain, liver, testis and epithelium.

Immunogen: Synthetic peptide derived from human Numb protein.

Purification Method: Ammonium Sulfate Precipitation.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.

References: 1. Susini, L., et al. 'Siah-1 binds and regulates the function of Numb.; Proc. Natl. Acad. Sci. U.S.A. 98:15067-15072(2001).

2. Verdi, J.M., et al. 'Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage.; Proc. Natl. Acad. Sci. U.S.A. 96:10472-10476(1999).

UniProt: P49757 (Human).

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX2353P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X2353P
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Wirt: Rabbit