Rabbit anti Human SPT16 (Intermediate Domain)

Rabbit anti Human SPT16 (Intermediate Domain), Polyclonal, IgG

Background: SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.

Positive Control: Recombinant proteins conjugated to OVA, GST, His tags and other.

Immunogen: Recombinant protein consisting of amino acids 321-640 of the human SPT16 protein conjugated to KLH.

Purification Method: Ammonium Sulfate Precipitation

Concentration: See vial for concentration

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

References: 1. Keller, D.M., et al. 'A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSPT16 and SSRP1.' Mol. Cell Biol. 2001, 7, 283-292

UniProt: Q9Y5B9

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX1584P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X1584P
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Immunoprecipitation, Western Blotting
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated