Rabbit anti-HURP/DLG7 Antibody, Affinity Purified

Stock Concentration: 200 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_055565.2

Uniprot ID: Q15398

Background: HURP/DLG7 (Hepatoma Up-Regulated Protein/Disks Large Homolog 7) is a member of the MAGUK (membrane-associated guanylate kinase) family of scaffolding proteins. There are seven DLG homologs in mammals that play important roles in regulating proliferation, epithelial cell polarity, cell adhesion, and synapse formation. HURP/DLG7 has been identified as a microtubule-associated protein (MAP) that colocalizes with the mitotic spindle and functions as a mitotic regulator. HURP/DLG7 is required for microtubule attachment and efficient capture of kinetochores, as well as timely chromosome congression. HURP/DLG7 is up-regulated in human cancer cells and may contribute to tumorigenesis.

Immunogen: Between 796 and C-terminus

• Artikelnummer: BEYA300-853A-T
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A300-853A-T
• Green Labware: Nein
• Verpackungseinheit: 10 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunoprecipitation, Western Blotting
• Isotyp: Whole IgG
• Human Gene ID: 9787
• Wirt: Rabbit