Rabbit anti Rat BAG-5

Rabbit anti Rat BAG-5, Polyclonal

Background: It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70Õs anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.

Immunogen: Synthetic peptide derived from the human BAG-5 protein.

Purification Method: Ammonium Sulfate Precipitation

Concentration: See vial for concentration

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

References: 1. Takayama,S., et al. 'An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.' J. Biol. Chem. 1999, 274: 781-786

UniProt: Q9UL15 (Human)

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX1596P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X1596P
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunohistochemistry (paraffin), Western Blotting
• Wirt: Rabbit
• Konjugat: Unconjugated