Rabbit anti-TIM3 antibody, clone SQab22265 (monoclonal)

Clone Number: SQab22265

Immunogen: A synthetic peptide corresponding to the sequence of Human TIM-3.

Concentration: n/a

Format: Purification with Protein A.

Storage buffer: PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.

Additional info: Application note: IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.Storage instruction: For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Applications: FC, IHC-P, WB

• Artikelnummer: SANMON240256
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON240256
• Verpackungseinheit: 100 ul
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin), Western Blotting, Flow Cytometry
• Wirt: Rabbit
• Konjugat: Unconjugated