Rabbit anti-XPF/ERCC4 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_005227.1

Uniprot ID: Q92889

Background: XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly.

Immunogen: Between 866 and C-terminus

• Artikelnummer: BEYA301-315A-T
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A301-315A-T
• Verpackungseinheit: 10 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunoprecipitation, Western Blotting
• Human Gene ID: 2072
• Wirt: Rabbit