RANK:RANKL TR-FRET Assay

Products from BPS Bioscience require a minimum order value above 400€

Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.

Description: The RANK:RANKL TR-FRET Assay is designed to measure the inhibition of RANK binding to RANKL. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing biotinylated RANK, RANKL, anti-His Tb donor, dye-labeled acceptor, and an inhibitor is incubated for one hour. Then, the fluorescence intensity is measured using a fluorescence reader.

Storage Stability: Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Annis, A., et al. J. Amer.n Chem. Soc., 2004 May; 126(4): 15495-15503.2. Yan, T., et al. J. Cell. Biochem. 2001 Aug; 83(2): 320-325.

• Artikelnummer: BPS79101-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 79101-1
• Green Labware: Nein
• Verpackungseinheit: 96 rxns.
• Mengeneinheit: PAK