RASIP1 Polyclonal Antibody, Rabbit

Abbreviation: RASIP1

Target Synonym: RAIN;RASIP1

Conjugation: Unconjugated

UNIProt ID: Q5U651

Background: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human RASIP1

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-92060-200
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92060-200
• Green Labware: Nein
• Verpackungseinheit: 200 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit