Recombinant Human Apolipoprotein(a)/Lp(a) protein (His tag)

Recombinant Human Apolipoprotein(a)/Lp(a) protein (His tag)
Artikelnummer
ELSPDMH100054-100
Verpackungseinheit
100 µg
Hersteller
Elabscience Biotechnology

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Abbreviation: Apolipoprotein;Lp

Target Synonym: APOA;Apolipoprotein(a);Apo(a);Lp(a);LPA;Lp(a)

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: P08519

Background: Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-Lp(a). Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.

Sequence: Asp1719-Arg2038

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.
Mehr Informationen
Artikelnummer ELSPDMH100054-100
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer ELA-PDMH100054-100
Green Labware Nein
Verpackungseinheit 100 µg
Mengeneinheit STK
Produktinformation (PDF) Download
MSDS (PDF) Download