Recombinant Human ATXN7L1 protein (His tag)

Abbreviation: ATXN7L1

Target Synonym: Ataxin-7-like protein 1;ATXN7L1;Ataxin-7-like protein 1;Ataxin-7-like protein 4

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: Q9ULK2

Background: ATXN7 is found in the cytoplasm of all the populations of neurons analyzed in control brains, but nuclear labeling is observed in some neurons with a frequency and intensity weakly correlated with the topography of lesions in patients. Ataxin-7 is a component of the Tata binding protein (TBP)-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA), which is implicated in several steps of transcriptional regulation such as histone acetylation/deubiquitinylation and recruitment of the preinitiation complex to promoters.

Sequence: Met 1- Ala 146

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100313-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100313-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK