Description: FGF-basic stands as one of the 23 recognized members within the FGF family. These proteins hold pivotal roles in prenatal development, postnatal growth, and tissue regeneration by fostering cellular proliferation and differentiation. FGF-basic, specifically, serves as a non-glycosylated growth factor with a penchant for heparin binding. Its expression spans across various tissues including the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells, and endothelial cells. FGF-basic transmits signals through FGFR 1b, 1c, 2c, 3c, and 4 receptors. The recombinant form of Human FGF-basic, comprised of 146 amino acid residues, yields a 16.4 kDa protein.
Expression System: E. coli
Molecular Weight: 16.4 kDa
Class: Recombinant
Endotoxin Concentration: <1 EU/µg
Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10^7 units/mg.
Form: Lyophilized
Contains: no preservative
Storage Conditions: -20°C
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: FGF2
Protein ID: P09038
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