Description: CNTF, initially identified as crucial for the survival of chick ciliary neurons in lab cultures, plays a significant role in supporting various neural cell types' survival. These include primary sensory neurons, motor neurons, basal forebrain neurons, and type 2 astrocytes. CNTF's importance extends across different species, showcasing its conserved nature and cross-species effectiveness. The synthetic form, Recombinant Human CNTF, comprises a 199 amino acid polypeptide (22.8 kDa), devoid of a hydrophobic N-terminal signal required for secretion.
Published Species: Human, Mouse, Rat, Hamster
Expression System: E.coli
Molecular Weight: 22.8 kda
Class: Recombinant
Form: Lyophilized
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: CNTF
Protein ID: P26441
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