Description: IL-11, a versatile cytokine, is synthesized by stromal cells like fibroblasts, epithelial cells, and osteoclasts. Its expression spans various tissues such as the thymus, lung, bone, connective tissue, and central nervous system. IL-11 holds a crucial regulatory role in hematopoiesis by stimulating the growth of myeloid, erythroid, and megakaryocyte progenitor cells. Additionally, it influences bone metabolism, suppresses the production of proinflammatory cytokines, and provides protection against gastromucosal injury. Recombinant Human IL-11 is a 19.3 kDa protein comprising 179 amino acid residues.
Expression System: E. coli
Molecular Weight: 19.3 kDa
Class: Recombinant
Endotoxin Concentration: <1 EU/µg
Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg.
Form: Lyophilized
Contains: no preservative
Storage Conditions: -20°C
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: IL11
Protein ID: P20809
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