Description: IL-15 serves as an immunomodulatory cytokine that triggers the growth of T lymphocytes, sharing numerous traits with IL-2. Its primary effects are directed towards T cells, aiding in their development, longevity, and activation. Moreover, IL-15 plays a crucial role in nurturing and activating natural killer (NK) cells. Elevated IL-15 levels have been associated with conditions such as rheumatoid arthritis, inflammatory bowel disease, and diseases linked to retroviruses like HIV and HTLV-I. In experiments, Human IL-15 has demonstrated biological activity on mouse cells, notably by stimulating the dose-dependent proliferation of mouse CTLL cells. This recombinant protein, consisting of 115 amino acid residues and weighing 12.9 kDa, mirrors these functions.
Expression System: E. coli
Molecular Weight: 12.9 kDa
Class: Recombinant
Endotoxin Concentration: <1 EU/µg
Activity: Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Form: Lyophilized
Contains: no preservative
Storage Conditions: -20°C
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: IL15
Protein ID: P40934
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