Recombinant Human MCM8 protein (His tag)

Abbreviation: MCM8

Target Synonym: DNA helicase MCM8;MCM8;Minichromosome maintenance 8

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: Q9UJA3

Background: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.

Sequence: Met 1-Ser 250

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100387-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100387-20
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK