Recombinant Human PCNA protein (His tag)

Abbreviation: PCNA

Target Synonym: ATLD2;cb16;Cyclin;DNA polymerase delta auxiliary protein;Mutagen-sensitive 209 protein;Polymerase delta accessory protein;Proliferating cell nuclear antigen

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P12004

Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Sequence: Met 1-Ser 261

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100277-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100277-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK