Recombinant Human PKAbetacat/PRKACB protein (His tag)

Abbreviation: PKAβcat;PRKACB

Target Synonym: cAMP-dependent protein kinase catalytic subunit beta;PRKACB;PKA C-beta

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: P22694

Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Sequence: Gly 2-Phe 351

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100360-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100360-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK