Recombinant Human PSMA / FOLH1 protein (His tag)

Abbreviation: PSMA;FOLH1

Target Synonym: Glutamate carboxypeptidase 2;FGCP;GCPII;mGCP;NAALADase I;PSMA;Cell growth-inhibiting gene 27 protein;Folate hydrolase 1;FOLH1;GCP2;FGCP;GCPII;Mgcp;NAALADase I;FOLH;mGCP;NAALAD1;NAALAdase;PSM;PSMA

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: Q04609

Background: Glutamate carboxypeptidase 2, also known as FOLH1, PSMA, belongs to the M28B subfamily and the peptidase M28 family. It is highly expressed in prostate epithelium and can be detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. PSMA involves in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, PSMA cleaves Gly-Pro-AMC. PSMA is stable at pH greater than 6.5.

Sequence: Tyr 471-Ala 750

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100287-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100287-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK