Recombinant Human SF3B3 protein (GST tag)

Abbreviation: SF3B3

Target Synonym: Splicing factor 3B subunit 3;SF3B3;Spliceosome-associated protein 130

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-GST

UNIProt ID: Q15393

Background: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Sequence: Glu 250-Phe 399

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100430-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100430-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK