Recombinant Human TGFBR2 protein (His tag)

Abbreviation: TGFBR2

Target Synonym: AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;TGFbeta-RII;TGFR-2;TGF-beta receptor type-2;TGF-beta type II receptor;TGFBR2;Transforming growth factor-beta receptor type II

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P37173

Background: TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.

Sequence: Thr 23-Gln 166

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100439-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100439-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK