Recombinant Human Urokinase/uPA protein (His tag)

Abbreviation: Urokinase;uPA

Target Synonym: Urokinase-Type Plasminogen Activator;U-Plasminogen Activator;uPA;PLAU;ATF;BDPLT5;QPD;u-PA;UPA;URK

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: P00749

Background: Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.

Sequence: Met1-Leu431

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDMH100158-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDMH100158-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK