Target Synonym: E3 ubiquitin-protein ligase XIAP;XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;Inhibitor of apoptosis protein 3;RING-type E3 ubiquitin transferase XIAP;X-linked inhibitor of apoptosis protein
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
UNIProt ID: P98170
Background: XIAP (X-chromosome linked inhibitor of apoptosis) is a member of the apoptosis (IAP) family of proteins that inhibit caspases. The BIR2 domain of XIAP inhibits caspase-3 and caspase-7. The ability of XIAP to inhibit caspases is prevented by SMAC/Diablo through binding to XIAP-BIR2 and -BIR3 domains.
Sequence: Met 1-Ser 497
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.