Recombinant Mouse FAP protein (His Tag)

Abbreviation: FAP

Target Synonym: 170 kDa melanoma membrane bound gelatinase;170 kDa melanoma membrane-bound gelatinase;DPPIV;FAP;FAPA;Fibroblast activation protein alpha;Integral membrane serine protease;SEPR;Seprase;FAPalpha;SIMP

Target Species: Mouse

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: P97321

Background: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2. Degrade also gelatin, heat-denatured type I collagen, but not native collagen type I and IV, vibronectin, tenascin, laminin, fibronectin, fibrin or casein. Have also dipeptidyl peptidase activity, exhibiting the ability to hydrolyze the prolyl bond two residues from the N-terminus of synthetic dipeptide substrates provided that the penultimate residue is proline, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. Natural neuropeptide hormones for dipeptidyl peptidase are the neuropeptide Y (NPY), peptide YY (PYY), substance P (TAC1) and brain natriuretic peptide 32 (NPPB).

Activity: Immunogen(E-AB-40349)

Sequence: Leu26-Gly349

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEM100025-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEM100025-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK