Recombinant Mouse HGF Protein (His Tag)

Abbreviation: HGF

Target Synonym: Hepatopoietin-A;Scatter factor;SF;Deafnes;Autosomal recessive 39;DFNB39;F-TCF;Hepatocyte growth factor

Target Species: Mouse

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: Q08048

Background: HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. It can also alter epithelium morphology by the induction of nectin-1 alpha ectodomain shedding, an adhesion protein component of adherens junctions.

Sequence: Gln33-Leu728

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDMM100019-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDMM100019-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK