Recombinant mouse IGF1/IGF-I/IGF-1 protein (His tag)

Abbreviation: IGF1;IGF-1

Target Synonym: IGF1;IGF-1;insulin-like growth factor 1;Insulin-like growth factor I;Somatomedin C;somatomedin-C

Target Species: mouse

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P05017

Background: nsulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.

Sequence: Ala 48-Met 153

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEM100099-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEM100099-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK