Recombinant Mouse Syndecan-4/Sdc4 protein (His tag)

Abbreviation: Syndecan-4;Sdc4

Target Synonym: AA959608;AW108331;ryudocan;Synd4;syndecan-4;SDC4;SYND4;Ryudocan core protein

Target Species: Mouse

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: O35988

Background: SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with a number of signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty.

Sequence: Met 1-Val 146

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDMM100020-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDMM100020-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK