Recombinant Rabbit IL1B protein(His tag)

Abbreviation: IL-1B

Target Synonym: IL-1 beta;Lymphocyte proliferation-potentiating factor;IL-1B

Target Species: Rabbit

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P14628

Background: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

Sequence: Ala117-Ser268

Purity: > 80 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEO100009-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEO100009-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK