Recombinant Rat FGG/Fibrinogen gamma chain protein (His tag)

Abbreviation: FGG;Fibrinogen gamma chain

Target Synonym: FIBG;Fibrinogen gamma chain;fibrinogen gamma-b chain

Target Species: Rat

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P02680

Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Sequence: Gln 26-Pro 445

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDER100078-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDER100078-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK