RediSolution™ (+)-JQ1 , CAS 1268524-70-4

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Biological Activity: (+)-JQ1 has been shown to inhibit BRD4 (BD1) with a Kd of 50 nM, and BRD4 (BD2) with a Kd of 90 nM.

CAS Number: 1268524-70-4

Description: (+)-JQ1 is a specific inhibitor of the BET family of acetyl-lysine recognition motifs, including the BRD2, BRD3, BRD4 and BRDT bromodomains.

Format: DMSO solution

Purity: ≥95% by HPLC

Storage Stability: Store at -20°C and avoid multiple freeze-thaw cycles to prevent decomposition.

Supplied As: 10 mM solution in anhydrous DMSO

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: Filippakopoulos P., et al. Nature. 468(7327):1067-73 (2011).Application Reference:1. BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen (2014)2. Dual kinase-bromodomain inhibitors for rationally designed polypharmacology (2014)

• Artikelnummer: BPS27403
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27403
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK