Product Type: Antioxidant
CAS No.: 501-36-0
MolecularFormula: C14H12O3
Molecular Weight: 228,25
Source: Synthetic
Purity: >98%
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Appearance: Off-White Solid
PubChem CID: 445154
Scientific Background: Resveratrol is a stilbenoid and a phytoalexin produced naturally by several plants. Its effects are numerous and include anti-cancer (1), anti-inflammatory (2), anti-fungal and has other beneficial cardiovascular effects.It has been proposed that Mn SOD is increased by the pathwayRESV-SIRT1/Nad+- FOXO3a- MnSOD (3). In terms of its anti-cancer properties, resveratrol modulates the transcription factor NF-KB and inhibition of the cytochrome P450 enzyme (1, 4).
References: 1. Leiro J., et al. (2005) Int Immunopharm. 5(2): 393-406.2. Gentilli M., et al. (2001) Life Sciences. 68(11): 1317-1321.3. Robb E.L., et al. (2008) Biochem Biophys Res Commun. 367(2): 406-412.4. Chun Y.J., Kim M.Y., Guengerich F.P. (1999) Biochem Biophys Res Commun. 262(1): 20-24.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.