rHuman IL-10 Protein

rHuman IL-10 Protein
Artikelnummer
ROC009-001-V47-0010
Verpackungseinheit
10 µg
Hersteller
Rockland

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Application Note: Human Interleukin-10 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Human Interleukin-10 in immunological assays.

Concentration Value: 0.1 mg/ml

General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Other Performance Data: Endotoxin Level: Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein. Biologic Activity: The activity is determined by the dose-dependant proliferation of mouse MC-9 cells and is typically less than 0.5 ng/mL.

Physical State: Lyophilized

Purity and Specificity: Interleukin-10 purity was determined to be greater than 90% as determined by reducing and non-reducing SDS-pAGE.

Background: Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-γ, TNF-α, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells. While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells. Recombinant human IL-10 is a non-glycosylated protein, containing 161 amino acids, with a molecular weight of 16.6 kDa.

Low Endotoxin: Yes

Other: User Optimized
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Artikelnummer ROC009-001-V47-0010
Hersteller Rockland
Hersteller Artikelnummer 009-001-V47-0010
Verpackungseinheit 10 µg
Mengeneinheit STK
Konjugat Unconjugated
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