rHuman TNF alpha Protein

rHuman TNF alpha Protein
Artikelnummer
ROC009-F01-W31-0050
Verpackungseinheit
50 µg
Hersteller
Rockland

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Application Note: Tumor Necrosis Factor alpha Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Tumor Necrosis Factor alpha in immunological assays.

General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Other Performance Data: Endotoxin Level: Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein. Biologic Activity: The activity is determined by the cytolysis of mouse L929 cells in the presence of Actinomycin D and is typically less than 0.05 ng/mL.

Physical State: Lyophilized

Purity and Specificity: Tumor Necrosis Factor alpha is produced with no animal-derived raw products, animal free equipment and animal free protocols. Purity was determined to be greater than 96% as determined by reducing and non-reducing SDS-PAGE.

Background: Tumor Necrosis Factor alpha (TNFα) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, NK-cells following their stimulation by bacterial LPS. TNFα activates signals through two receptors, TNFR1, which is expressed on most cell types, and TNFR2, which is expressed mainly on immune cells. TNFα can have many functions including, to stimulate of phagocytosis in macrophages, to chemoattract neutrophils, to increase insulin resistance and to induce fever. Recombinant human TNF-α is a non-glycosylated protein, containing 158 amino acids, with a molecular weight of 17.5 kDa.

Low Endotoxin: Yes

Other: User Optimized
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Artikelnummer ROC009-F01-W31-0050
Hersteller Rockland
Hersteller Artikelnummer 009-F01-W31-0050
Verpackungseinheit 50 µg
Mengeneinheit STK
Methode SDS-PAGE
Konjugat Unconjugated
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