RNF34 (N Terminus) blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89815.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Concentration:

Background: The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]

Region Sequence: KAGATSMWASCC

Full Name: ring finger protein 34, E3 ubiquitin protein ligase

• Artikelnummer: GTX89815-PEP-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX89815-PEP-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
• Methode: ELISA, Blocking, Affinity Purification
• Human Gene ID: 80196