Rotundine, CAS 483-14-7

Product Description: Rotundine is an antagonist of dopamine D1, D2 and D3 receptors with IC50s of 166 nM, 1.4 μM and 3.3 μM, respectively. Rotundine is also an antagonist of 5-HT1A with an IC50 of 370 nM.

Applications: Neuroscience-Neuromodulation

Formula: C21H25NO4

References: [1]Wang JB, et al. l-tetrahydropalamatine: a potential new medication for the treatment of cocaine addiction. Future Med Chem. 2012 Feb;4(2):177-86./[2]Liu YL, et al. Effects of l-tetrahydropalmatine on locomotor sensitization to oxycodone in mice. Acta Pharmacol Sin. 2005 May;26(5):533-8.

CAS Number: 483-14-7

Molecular Weight: 355.43

Compound Purity: 99.96

Research Area: Neurological Disease

Solubility: DMSO : ≥ 100 mg/mL/H2O : < 0.1 mg/mL

Target: 5-HT Receptor;Dopamine Receptor

• Artikelnummer: MEXHY-N0096-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0096-10.1
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK