SB202190, CAS 152121-30-7

p38 MAP kinase inhibitor

Product Type: Inhibitor

CAS No.: 152121-30-7

MolecularFormula: C20H14FN3O

Molecular Weight: 331,3

Source: Synthetic

Purity: ≥98% (TLC)

Solubility: Soluble in methanol, DMSO or acetone; slightly soluble in ethyl acetate

Appearance: Pale yellow solid

PubChem CID: 5353940

Scientific Background: SB202190 is a highly selective and potent inhibitor of p38 MAP kinase. Specifically, it binds within the ATP pocket of the active kinase and selectively inhibits the p38α and β isoforms. It has been shown to induce apoptosis. SB202190 is cell-permeable.

References: 1. Nemoto S., Xiang J., Huang S., & Lin A. (1998) J. Bio. Chem. 273(26): 16415–16420.2. Karahashi H., Nagata K., Ishii K., & Amano F. (2000) Biochimica Et Biophysica Acta. 1502(2): 207–223.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-473-5MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-473-5MG
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK