Scopolamine, CAS 51-34-3

Formulation: A solid

Formal Name: αS-(hydroxymethyl)-benzeneacetic acid, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester

Purity: ≥98%

Formula Markup: C17H21NO4

Formula Weight: 303,4

Shelf life (days): 1460

CAS Number: 51-34-3

Notes: Scopolamine is an alkaloid that has been found in D. stramonium and has diverse biological activities.{31350,27107,46375,61178,18345,66637} It is an antagonist of muscarinic acetylcholine receptors (mAChRs; Kis = 0.19, 1.41, and 0.18 nM for the rat M1, M2, and M3 receptors, respectively).{27107} Scopolamine reduces acetylcholine-induced contractions in isolated guinea pig ileum (IC50 = 8.1 nM).{46375} It inhibits tremors induced by the mAChR agonist oxotremorine (Item No. 35707) in mice (ED50 = 0.23 mg/kg). Scopolamine increases fine motor activity counts and ambulatory activity in rats in a home-cage activity test (ED50 = 0.12 mg/kg for both).{61178} It has been used to induce learning deficiencies or amnesia in animal models.{18345,66637} Formulations containing scopolamine have been used in the treatment of motion sickness and postoperative nausea and vomiting. This product is also available as an analytical reference standard (Item No. 14108).

• Artikelnummer: CAY40307-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 40307-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK