Sheep anti bcl-2

Sheep anti bcl-2, Polyclonal, IgG

Background: Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14;18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter.

Purification Method: Ammonium Sulfate Precipitation.

Source: Sheep were immunized with full length recombinant bcl-2 protein.

References: 1. Chida, Y., et al. 'The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice.' Gut 2005, 54, 994-1002 (Product specific).

UniProt: P10415.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAA105P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: A105P
• Green Labware: Nein
• Verpackungseinheit: 250 µg
• Mengeneinheit: STK
• Reaktivität: Human, Rat (Rattus), Dog (Canine)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting
• Isotyp: IgG
• Wirt: Sheep